Winter's Hidden Bone Health Risk: The Vitamin D-Fracture Connection

A review of Seasonal Periodicity of Serum Vitamin D and Parathyroid Hormone, Bone Resorption, and Fractures: The Geelong Osteoporosis StudyPasco JA, Henry MJ, Kotowicz, MA, et al. https://onlinelibrary.wiley.com/doi/epdf/10.1359/jbmr.040125

Today, I want to share research from the Geelong Osteoporosis Study, which reveals a connection between winter months and fracture risk. Hopefully, this will provide some insight into guiding your patients.

The Winter Chain Reaction

Picture this: as winter sets in and sunlight diminishes, your body kicks off a cascade of events directly impacting your bone health. Here's what happens:

First, reduced UV radiation leads to a drop in vitamin D levels (with about a one-month delay). This triggers an increase in parathyroid hormone (PTH) levels, which then accelerates bone resorption – essentially, your body starts breaking down bone tissue faster than usual.

The end result? A significantly higher risk of fractures during winter months.

The Numbers Don't Lie

The research findings are striking. During winter's vitamin D low point:

  • 60% of study participants had vitamin D levels below the recommended threshold

  • The proportion of falls resulting in fractures jumped to 67.5% (compared to 58.2% in summer)

  • Hip and wrist fractures peaked 1.5-3 months after vitamin D reached its lowest levels

The study suggests that if we maintain summer vitamin D levels year-round, we could potentially reduce hip fractures by 16% and wrist fractures by 30%. Now, I am a bit skeptical about these numbers. However,they do make me think about increasing the vitamin D in my patients who have a history of very low vitamin D. 

Why This Matters

This isn't just about numbers – it's about real people and preventable injuries. While previous studies focused mainly on institutionalized elderly populations, this research shows that seasonal vitamin D insufficiency affects the broader community. It impacts fracture risk in two ways:

  1. Increasing the likelihood of falls

  2. Reducing bone strength during critical winter months

Looking Forward

To me, this research suggests that we should probably pay attention to varying levels of vitamin D in our highest-risk patients. While more research is needed to confirm whether vitamin D supplementation can effectively prevent this seasonal pattern of fractures, the evidence suggests it could be a valuable preventive strategy.

For my patients and colleagues in bone health, these findings highlight the importance of seasonal awareness in fracture prevention strategies. It's not just about maintaining bone density – it's about understanding and counteracting the seasonal factors that put our bones at risk.

Remember, bone health isn't just a summer concern. By understanding these seasonal patterns, we can better protect ourselves and our patients year-round.

Jared Torkelson, PA-C

Jared is a Physician Assistant in the Orthopedic and Sports Medicine department within Mayo Clinic Health System. He specializes in adult lower extremity reconstruction, trauma, and treatment of osteoporosis in the setting of fragility fractures. He operates the only Fracture Liaison Service (FLS) within the Mayo Clinic Health System. He is an instructor of Orthopedics through the Mayo Clinic Alix School of Medicine and has given presentations on starting FLS programs both regionally and nationally.

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Post-fracture Care: Not Just a Band-Aid